Spring Creek is an unincorporated community in Madison County, Tennessee, United States. The zipcode is 38378. Spring Creek was named for a nearby stream of the same name, a tributary of the Middle Fork of the Forked Deer River, after a post office opened there in the spring of 1824. A municipal charter was granted in January 1854, an…Spring Creek is an unincorporated community in Madison County, Tennessee, United States. The zipcode is 38378. Spring Creek was named for a nearby stream of the same name, a tributary of the Middle Fork of the Forked Deer River, after a post office opened there in the spring of 1824. A municipal charter was granted in January 1854, and the West Tennessee Baptist Male Institute was chartered in Spring Creek that March. The Institute, later called Madison College, continued operation until it burned down in February 1876.