“Even though drugs like tirzepatide and semaglutide work really well—better than anything we have ever seen—we still have people who don't respond to them,” said Dr. Aronne.

The tirzepatide group had more injection-site reactions than the semaglutide group, which is consistent with other SURMOUNT trials. 14,20 In the current trial, no participants were reported to ...

Participants using tirzepatide lost 50.3 lbs. (22.8 kg) and participants on Wegovy lost 33.1 lbs. (15.0 kg), on average SURMOUNT-5, a first-of-its-kind head-to-head trial, compared tirzepatide, a ...

Of adults receiving tirzepatide, 94.4% lost at least 5% body weight during the treatment period. From study entry to 84 weeks, the tirzepatide group lost a total of 26.6% body weight.

A new weight loss drug is more effective than medications such as Ozempic and Wegovy, new research suggests. Tirzepatide, which is sold under the brand names Mounjaro and Zepbound – which treat ...

Even though drugs like tirzepatide and semaglutide work really well, better than anything we have ever seen, we still have people who don't respond to them. So, moving forward, we want to keep ...

Researchers collected data from the five SURPASS trials, which assessed the effects of tirzepatide among people with type 2 diabetes. Tirzepatide was compared with placebo in SURPASS-1 and SURPASS ...

In the latter trial, 15 mg of tirzepatide reduced A1C by 2.59% and body weight by 10.9 kg (11.6%) from baseline. Furthermore, when receiving the highest dose, 62.4% of SURPASS-5 trial participants ...

“Even though drugs like tirzepatide and semaglutide work really well—better than anything we have ever seen—we still have people who don't respond to them,” said Dr. Aronne.