San Francisco 49ers running back Isaac Guerendo (hamstring) was looking like a sure-fire league-winner after a highly ...

RB Jordan Mason filled in admirably to start the year, but he was hit with a shoulder injury in Week 6 that he battled until ...

The San Francisco 49ers are going to have a fourth different starting running back this season according to a report from ...

The 49ers will have to start their fourth different running back this Sunday against the Miami Dolphins. That's because ...

San Francisco 49ers running back Isaac Guerendo appeared on Wednesday's injury report due to a hamstring issue sustained ...

Isaac Guerendo was initially uncertain for Thursday night, but the rookie looks like he might give it a go. Here's the latest ...

The San Francisco 49ers running back is questionable with a sprained foot, but per ESPN’s Adam Schefter: he “plans to play” ...

Coach Kyle Shanahan said Monday that the 49ers expect Guerendo (foot/hamstring) to practice Thursday, Nick Wagoner of ESPN.com reports.

Well this isn't good. 49ers rookie Isaac Guerendo is nursing a new injury. Kyle Shanahan revealed Guerendo was held out of ...

The 49ers won’t be down to their 4th-string running back tonight against the Rams as Isaac Guerendo is expected to play ...

ESPN insider Adam Schefter reported that San Francisco 49ers rookie running back Isaac Guerendo is unlikely to play against ...

“49ers rookie RB Isaac Guerendo plans to play Thursday night vs. the Rams despite his sprained foot that has left him being ...