Arizona’s 24-23 win on Oct. 6 of last season, a game in which the 49ers led 23-10, helped chart the path to a 6-11 season.

Dallas Cowboys | New York Giants | Philadelphia Eagles | Washington Commanders NFC North: Chicago Bears | Detroit Lions | Green Bay Packers | Minnesota Vikings NFC South: Atlanta Falcons | Carolina Panthers | New Orleans Saints | Tampa Bay Buccaneers NFC West: Arizona Cardinals | Los Angeles Rams | San Francisco 49ers | Seattle Seahawks

With a 3rd & 5 at the Arizona 40-yard line, a run was the right call to get San Francisco with a better short-distance situation on fourth down. Christian McCaffrey got three yards, setting up the 4th & 2 pass from Mac Jones to Ricky Pearsall. Two plays later, the 49ers scored on a 1-yard play-action pass to Kyle Juszczyk, taking a 13-6 lead.

The 49ers managed to edge out a win over the Arizona Cardinals on Sunday. Coach Kyle Shanahan admitted postgame that he regretted sticking with his fourth-and-goal call, which failed to convert a 49ers touchdown on the Arizona 1-yard line with 20 seconds left in the third quarter,

It was an injury-riddled afternoon of attrition, slow-moving masses of men in a battle of who could go backward less, leading Kyle Shanahan to fittingly call the Niners' three wins to open the season - and take an early lead in the NFC West - as "grimy."

Kyle Shanahan revealed why San Francisco is benefitting from its rookie defenders during an interview on NBC Sports Bay Area's "49ers Game Plan."

Eddy Pineiro drilled a 35-yard field goal as time expired to lift the San Francisco 49ers to a 16-15 win over the Arizona Cardinals on Sunday afternoon in Santa Clara, Calif.