It has something to do with a sliding interaction between actin and myosin. In 1954, scientists published two groundbreaking papers describing the molecular basis of muscle contraction.

The conformation of myosin V when strongly bound to actin has been revealed by electron ... for the swinging cross-bridge model of muscle contraction proposed in 1969. Although muscle researchers ...

Muscle contraction occurs when these myofilaments ... smooth muscle cells shorten via the movement of actin and myosin myofilaments. The one exception of an involuntary muscle is the myocardium ...

This occurs through a physiologic process that leads to an increased number of contractile proteins (actin and myosin) in ...

Our lab’s investigations of cardiac muscle contraction focus on the effects of cardiomyopathy-causing amino acid substitutions on myosin’s mechanical and ... We are also investigating actin filament ...