Beta-blockers (a class of drugs used to treat high blood pressure), such as Lopressor (metoprolol) or Tenormin (atenolol), can cause an additive effect with amlodipine. This, in turn, can cause ...

Use of the drug increased exercise capacity and provided additional antianginal relief to symptomatic patients with severe chronic angina taking standard doses of atenolol, amlodipine, or diltiazem.