Myotonic dystrophy type 1 (DM1) is the most common adult-onset form of muscular dystrophy and a condition that severely ...

We have demonstrated that overexpression of an inhibitory component of the β-adrenergic signaling pathway suppresses AV nodal conduction ... can modify the cardiac electrical substrate implicated ...

Heart attacks and cardiac arrest differ in causes, symptoms, and treatments. Learn how recognizing these emergencies improves ...

An electrocardiogram is a picture of the electrical conduction of the heart. By examining changes from normal on the ECG, clinicians can identify a multitude of cardiac disease processes.

Cardiovascular disease (CVD) is the leading cause of death and disease burden worldwide. Macrophages are important components of the internal immune cells, which profoundly affects the internal ...

Heart block is a type of arrhythmia. It means electrical signals in the heart are not working as they should, delaying the conduction of the heart beat. First-degree heart block is the least ...

Myotonic Dystrophy Type 1 (DM1) is the most common adult-onset form of muscular dystrophy and a condition that severely affects multiple organs including skeletal muscle, heart, brain and the ...

The research team aimed to resolve conduction slowing for the first time through the insertion of a novel gene into heart muscle cells. "The search for a gene therapy is not a new one but until ...

Calcium is essential for muscle contraction and cardiac electrical conduction, and its deficiency leads to heart failure. Vitamin deficiencies also increase the risk of sudden cardiac arrest.

More information: SCN10A-short gene therapy to restore conduction and protect against malignant cardiac arrhythmias, European Heart Journal (2025). DOI: 10.1093/eurheartj/ehaf053 Provided by ...