Nature2mon
Molecular basis for Rac2 regulation of phagocyte NADPH oxidase
A Rac GTPase–regulated multiprotein NADPH oxidase is critical for the formation of reactive oxygen species (ROS) in phagocytic leukocytes and other nonphagocytic cells. NADPH oxidase reduces ...
pharmaphorum10mon
Prime editing comes of age as FDA clears human trials
application for ex vivo use of its Prime Editor platform to correct a mutation associated with chronic granulomatous disease (CGD), which leaves patients vulnerable to recurrent life-threatening ...
Business Wire1mon
Ensoma Receives Rare Pediatric Disease and Orphan Drug Designations for EN-374 for Treatment of Chronic Granulomatous Disease
Chronic granulomatous disease (CGD) is a rare and severe genetic disorder, which significantly impairs the immune system. It leaves patients vulnerable to recurrent and severe bacterial and fungal ...