Heparin, when complexed with antithrombin III, inhibits free thrombin and factor Xa. Warfarin depletes the ... and can continue to stimulate the coagulation cascade. [12] Dr. Gulseth has been ...
For patients undergoing elective hip- and knee-replacement surgery, the current options for prophylaxis of VTE include low-molecular-weight heparin ... in the coagulation cascade: thrombin ...