They become parents together when they adopt their oldest daughter, Zola Grey Shepherd, from Africa. Their second child, Derek Bailey Shepherd, is born to the pair in 2013.

Grey's Anatomy kept 1 Derek's family secret closely guarded, but the shocking events of season 21's midseason finale can finally reveal the truth.

Now this would be the ultimate twist. Some ‘Grey’s Anatomy’ fans believe that Derek Shepherd is actually alive after all these years. Let’s break down this theory.

Actor Patrick Dempsey departed Grey's Anatomy years ago, but some are unclear about which episode his character Derek died in and why he left.

Richard Webber, Preston Burke, and Derek Shepherd each aspired to be Chief, facing their own challenges. Miranda Bailey, Alex Karev, and others took on the Chief role with varying successes and ...

Meredith and Derek's love story on "Grey's Anatomy" lasted long after Patrick Dempsey exited the series on season 11. Here's the complete timeline.

In the wake of Dr. Derek Shepherd’s shocking death last week on “Grey’s Anatomy,” creator Shonda Rhimes spent two hours Thursday expounding on a thought that Joni Mitchell once condensed ...

If fans were upset over Derek Shepherd's death, they won't be pleased with how Grey's Anatomy handled Derek's funeral — or lack thereof. While I'd been hoping, along with many others, that his ...

Addison struggles with the absence of her ex-husband, Patrick Dempsey's Derek Shepherd, from Grey Sloan after reconnecting with Meredith during a complicated surgery.

Real or fictional, it’s never easy to accept the loss of someone you care about. When Derek Shepherd was killed off in ‘Grey’s Anatomy,’ fans took to Twitter to react.