Derek Shepherd returned to Grey’s Anatomy Season 17 during episode 2, “The Center Won’t Hold.” In the last few minutes of the episode, Dr. Cormac Hayes (Richard Flood) found Meredith ...

A smiling Derek lovingly looks back at her, ... As Derek Shepherd would say, 'It’s a beautiful day to save lives.'" Grey's Anatomy airs Thursdays at 9 p.m. ET/PT on ABC.

When Grey's Anatomy took off as a cultural phenomenon in the mid-2000s, Patrick Dempsey's Dr. Derek Shepherd also swiftly became one of the biggest heartthrobs on television. Nicknamed "McDreamy ...

After we said goodbye to Patrick Dempsey‘s dreamy doctor alter ego, Derek Shepherd, in 2015, we didn't think we'd ever see McDreamy again.

She looked around, dazed, and saw a man smiling and waving at her. Upon closer look, Meredith (and screaming fans at home) realized it was Meredith's late husband, Dr. Derek "McDreamy" Shepherd.

Former ‘Grey’s Anatomy’ cast member Patrick Dempsey (Derek Shepherd) opens up about the ‘McDreamy’ nickname following his return in season 17.

How is this for symbolism — the Season 17 premiere of ABC‘s Grey’s Anatomy, which featured the surprise return of Patrick Demsey as Derek Shepherd, added +3.09 million viewers after three ...

Derek: Hey. Meredith: Hey. What are you doing here? (Smiling) Derek: You didn’t think I was gonna let you do this by yourself, did you?

Shonda Rhimes attends the press room at the 2015 Writers Guild Awards on Feb. 14 in Los Angeles, Calif. She explained why Derek Shepherd had to die on ‘Grey’s Anatomy’ at TCA on Tuesday.