Colorectal cancer (CRC) is the third most common cancer worldwide. More troubling is that what had been a stable incidence is now rising, particularly early-onset CRC – in the birth cohort of the ...

The rise of early-onset colorectal cancer (CRC) may be associated with mutational signatures left from childhood exposure to colibactin-producing bacteria. (Nature) Results of a survey suggested ...

Early-onset CRC has become increasingly common. ... irritable bowel syndrome, hemorrhoids, or anal fissures over CRC in a young patient. ...

CRC also exemplifies the challenges of understanding early-onset cancer, as it can be affected by genetic factors, notably Lynch syndrome, as well as lifestyle and changes in the environment.

The rise in early-onset cancers like CRC has puzzled many clinicians and cancer researchers. After all, cancer has been seen as a disease of old age, and over the last few decades, significant ...

Early-onset cancers require multidisciplinary care, ... (MSI and MSS EO-CRC), rates of gPVs range from 9% to 26.4%. 63,64 Although LS is the most common genetic syndrome associated with EO-CRC, there ...

Despite this, large-scale genome-wide association studies (GWAS) with gene-environment interaction analyses could better define the contribution of genetic factors to early-onset CRC presentation.

There were 120 early-onset CRC and 518 late-onset CRC cases who were included in the study, with the mean (SD) age of diagnosis being 43.5 (4.5) years and 63.2 (8.3) years respectively.

Early-onset CRC ; Early-onset CRC. Letter March 06, 2025. facebook twitter whatsup linkded email. Early-onset CRC. Colorectal cancer (CRC) is increasingly being diagnosed among younger individuals ...