Angelman syndrome is caused by a large deletion of the region of the maternal chromosome that contains UBE3A, or by a DNA sequence change (mutation) in the UBE3A gene inherited from the mother.

presented results of both in vitro and in vivo studies at the November 2024 FAST Global Summit on Angelman syndrome. The team will be using the new CIRM grant to prepare a pre-IND package ...

"So FAST (Foundation for Angelman Syndrome Therapeutics) and the Angelman Association in Australia worked really hard on our ...

Considering taking supplements to treat angelman syndrome? Below is a list of common natural remedies used to treat or reduce the symptoms of angelman syndrome. Follow the links to read common ...

MONTROSE, Mich. (WJRT) - A Mid-Michigan family is raising money to help their 6-year-old boy with a rare genetic disorder. After spending a few months looking for action figures and fun items, Kristin ...

Ionis has committed to a phase 3 programme for its antisense therapy for rare genetic disorder Angelman syndrome, just weeks after Biogen decided against exercising an option to license the drug.

We each get two copies of every gene - one copy from each of our parents. But what happens when one of these genes has been "turned off", or imprinted, and the remaining gene is defective?

"Angelman Syndrome is a neurogenetic disorder," said Weston's mother Felicia Warner. "It affects a lot of different things. It affects their balance, a very high percentage has seizures ...