Scientific organizations recently called for a 10-year ban on human germline editing. But will we ever be ready? And how ...

Those include BRCA1 and BRCA2, which occur in about one of every 500 women and confer an increased risk of breast or ovarian cancer, and rarer mutations in a gene called TP53 that causes a disease ...

Key Takeaways. Hereditary breast cancer results from inherited mutations, primarily in BRCA1 and BRCA2, increasing lifetime cancer risk. Additional genes like TP53, PTEN, PALB2, CHEK2, and ATM ...

Unlike so-called somatic gene editing, where one type of cell or tissue (the one where a mutation is wreaking the most havoc and causing disease) is targeted for modification, editing an embryo ...

Procedure of gene therapy. One of the first hurdles of gene therapy is successful introduction of the corrected gene into the human cells. Once introduced, the gene needs to be incorporated into ...

Mosaicism develops when cells within the same person are genetically different. Find out what causes these differences, how it may affect you, and more.

In December, the FDA approved the first two cell-based gene therapies for treating sickle cell disease: Casgevy and Lyfgenia. And, like any emerging medical technology, the initial use of the ...

Families of those who have sickle cell disease in the Philadelphia area are pushing for more research and a cure.

A new study by researchers at the Hebrew University of Jerusalem (HU) has revealed unexpected and sex-specific effects of germline regulation on longevity.

Some doctors told him he'd live with the disease forever, but Khaled Alsheebani never stopped believing treatments would advance one day.