Mutations that happen throughout a person’s life may contribute to disease more than we realized. In the summer of 2018, ...

Researchers at Dana-Farber Cancer Institute collaborated with multiple institutions to pinpoint rare germline structural ...

A new paper in Genome Biology and Evolution finds that the link between paternal age and rare congenital disorders is more complex than scientists had previously thought.

Cancer is primarily a genetic disease that is clonal in nature. It usually starts when a single cell acquires a series ... can be passed on through the germ line (i.e., inherited from one's ...

Metastasis we believe is, at least in part, a hereditary disorder. We have been so focused on the cancer cells, the 'seeds', that we've ignored the germline-;'the soil'. It's now clear that ...

a hereditary disorder," says Sohail Tavazoie, the Leon Hess Professor at Rockefeller. "We have been so focused on the cancer cells, the 'seeds', that we've ignored the germline -- 'the soil'.