This means looking out for "crusting and healing of all prior blisters and open sores in the skin," says Oza. More: Hand, foot, and mouth disease can be painful and inconvenient. Here's what it is.

Hand, foot and mouth disease (HFMD) is a very common viral infection that predominantly affects children under the age of 5, but it can also strike adults. It is characterized by fevers ...

In the skin rash stage, though, you can prevent infection by allowing blisters to heal naturally—avoid picking or scratching them. You can also do things to prevent hand, foot, and mouth disease ...