The Marfan Foundation and Baylor College of Medicine are conducting the multicenter Aortic Valve Operative Outcomes in Marfan Patients study (AVOMP) to compare the outcomes of aortic valve-sparing ...

Marfan syndrome is a genetic disorder that affects the heart's largest artery, the aorta. Studies were going on to get to the bottom of the disease and researchers at Johns Hopkins University have ...

That’s what it looks like. The aorta wall is made up of three layers of tissue. In people with Marfan syndrome, the glue that ...

F31HL163924), the Marfan Foundation, the Loeys-Dietz Syndrome Foundation and the Johns Hopkins Broccoli Center for Aortic Diseases.

The standard treatment for the connective tissue disorder Marfan's syndrome (MFS) is β-blockade, aimed at reducing aortic wall stress. Angiotensin II type 1 and 2 receptors (AT 1 and AT 2 ...

Connective tissue disorders such as Marfan’s syndrome have a significantly increased risk of aortic dissection. The onset of symptoms in aortic dissection are usually sudden without warning.

have a parent, sibling, or child who has a thoracic aortic aneurysm or who has experienced a rupture of an aneurysm or an ...

Marfan syndrome (MFS) is a heritable multisystemic disorder with a spectrum of clinical manifestations primarily linked to variants in the Fibrillin-1 ...

At this time, recruitment for extended follow-up is complete. Manifestations of the Marfan syndrome appear in many parts of the body, especially in the bones and ligaments (the skeletal system), the ...