Currently, the standard treatment for CGL involves daily injections of metreleptin, a synthetic version of the hormone leptin, which is naturally produced exclusively by fat tissue. However ...

Clinical study I: Body Weight, Metabolic, and Immune Responses to Metreleptin Versus Placebo Treatment in Obese Hyperleptinemic Subjects with Diabetes No Differential Activation of MAPK Signaling ...

Novelion Therapeutics’ Myalepta (metreleptin) developed for the ultra-rare condition lipodystrophy has been approved by the European Commission, giving patients the first treatment to improve ...

Takeda paid the San Diego–based biotech $75 million upfront for Symlin/metreleptin combination as part of an agreement that could exceed $1 billion if certain development and sales-dependent ...