A patent foramen ovale or PFO is a defect in the wall between the two upper chambers of the heart. This defect is actually an incomplete closure of the atrial wall that results in a flap or valve-like ...

Marco R. Di Tullio; Peter C. Block, M.D., F.A.C.C. However, the risk of first-ever stroke in asymptomatic subjects with PFO in the general population has not been clearly established. This ...

Patent foramen ovale (PFO) is an interatrial communication at the level of oval fossa caused by the incomplete or missed fusion of the septum primum and septum secundum after birth. PFO has a ...

This study presents the first use of cryoablation, a minimally invasive procedure that uses extreme cold, to induce PFO closure. Co-lead investigator of the study Jiang Deng, MMed, Department of ...

Learn about the groundbreaking research on evidence-based care at Toronto General Hospital Research Institute. Understand the ...