Patrick Dempsey revealed that he is often recognized more for 'Can't Buy Me Love' than for 'Grey's Anatomy,' despite the 20 years between the two.

Patrick and Jillian Dempsey shared sweet notes to each other on Wednesday for their 25th wedding anniversary.

Patrick Dempsey, who portrayed Dr. Derek "McDreamy," reacted to former "Grey's Anatomy" costar Ellen Pompeo leaving the show after 19 seasons.

Patrick Dempsey and his wife, Jillian Dempsey, are celebrating a milestone anniversary! On Wednesday, July 31, the Grey's Anatomy alum, 58, paid tribute to his partner as he marked their 25th ...

Is Patrick Dempsey Returning For Scream 7? Her return could be the perfect opportunity to bring back Dempsey, especially with the small seeds being planted that he’s still out there somewhere in ...

Patrick "McDreamy" Dempsey credits his acting career for helping him prepare for his return to racing. Fans can follow that journey in a new documentary.

Being named People’s Sexiest Man Alive is a McDreamy come true for Patrick Dempsey. The former “Grey’s Anatomy” star said he was getting ready to take a flight when he found out the ...

People's newest "Sexiest Man Alive" revealed Tuesday that his family "laughed quite hard" after the "Grey's Anatomy" star told them the news.

Patrick Dempsey opens up in an exclusive interview with PEOPLE about his mom Amanda Dempsey's cancer diagnosis. He saw firsthand the impact the disease can have on families. The actor's mother was ...

'Dexter: Original Sin' star Patrick Gibson and creator Clyde Phillips break down the Season 1 finale.

Former "Grey's Anatomy" star Patrick Dempsey says the long-running medical drama has "inspired" so many people to go into the medical profession.

Patrick Dempsey has praised Grey's Anatomy for how it has inspired people to get into medical professions. The actor, who played Derek Shepherd/McDreamy in the show between between 2005 and 2015 ...