Memory of a Killer, which features Patrick Dempsey as a hit man with early onset Alzheimer’s, has added an actor from The 100 ...

The return of Patrick Dempsey to network television sees him play a character whose difficult story is crueler than Derek's ...

Patrick Dempsey revealed that he is often recognized more for 'Can't Buy Me Love' than for 'Grey's Anatomy,' despite the 20 years between the two.

Patrick Dempsey wanted to return for 'Scream 7,' but now he explains why it didn't happen.

Patrick and Jillian Dempsey shared sweet notes to each other on Wednesday for their 25th wedding anniversary.

Patrick Dempsey and his wife, Jillian Dempsey, celebrated their twin sons Darby and Sullivan's high school graduation May 30. See photos from their big day!

Patrick Dempsey named official face of TAG Heuer Eyewear, showcasing sleek designs inspired by motorsport and luxury craftsmanship.

Patrick Dempsey says his eyes were opened when his mom was diagnosed with cancer. In an exclusive conversation with PEOPLE, the actor, 58, speaks candidly about his mom Amanda Dempsey's cancer ...

Patrick Dempsey posts rare photo of twin sons at graduation: ‘So proud of you boys' Dempsey attended the ceremony with his wife, Jillian Dempsey, and their daughter Talula.

NPR's Leila Fadel talks with actor Patrick Dempsey about his efforts to raise money for cancer treatment and prevention.