Purpose: The mechanism of action and pharmacokinetics of sirolimus when used as part of a drug-eluting stent (DES) and the efficacy and cost of using DESs versus bare-metal stents are discussed.
Fyarro consists of sirolimus albumin-bound particles, and is administered as an intravenous (IV) infusion twice a month. The drug won US Food and Drug Administration (FDA) approval in 2021 for the ...