Purpose: The mechanism of action and pharmacokinetics of sirolimus when used as part of a drug-eluting stent (DES) and the efficacy and cost of using DESs versus bare-metal stents are discussed.

Rapamune (sirolimus) is a brand-name drug that’s prescribed to help prevent kidney transplant rejection and to treat a rare lung condition. It’s used in adults and certain children.

Expanded conditional approval allows drugs that are undergoing their final clinical trial assessment and are supported by ...

With sirolimus-coated balloons gathering global ... trial comparing our device against paclitaxel drug-coated balloons (DCBs), which demonstrated non-inferiority--we are proud to announce the ...