A new study has pointed out that Molnupiravir treatment increases the ratio of transition to transversion mutations in COVID-19 patients and that the treatment does not appear to induce resistance ...

A transition mutation occurs when one purine is replaced by the other purine or when pyrimidines are switched. A transversion mutation is replacement of a purine with a pyrimidine or vice versa ...

Interestingly, 76.2% (16/21) of transversion mutations were found in FMTC/MEN2 patients, whereas 66.7% (12/18) of transition mutations were in sporadic MTC. Synonymous mutations were found in 12 ...

Most of the mutations observed are of the C:G > T:A transition type; however, the amino acid–altering mutations were transversion mutations. KIT exon 11 mutations were not identified in any of ...

By coupling mOsMPG with a transactivation factor VP64, rAKBE04 could enable simultaneous A-to-G and A-to-T transition and transversion base editing in rice stable lines. Advanced Search.

In this webinar, Dr. David Liu describes the development of two approaches to precision genome editing—base editing and prime editing—that do not require double-strand DNA breaks (DSBs).