Patrick Dempsey ’s role as McDreamy — a.k.a. Dr. Derek Shepherd — on Grey’s Anatomy might be his most iconic, but it’s not always the one he’s recognized for the most.

Patrick Dempsey revealed that he is often recognized more for 'Can't Buy Me Love' than for 'Grey's Anatomy,' despite the 20 years between the two.

Silver fox Patrick Dempsey has been named People’s Sexiest Man Alive for 2023. While it has been a long time coming for the 57-year-old to earn the spot, not everyone is happy with the choice ...

Patrick Dempsey posts rare photo of twin sons at graduation: ‘So proud of you boys' Dempsey attended the ceremony with his wife, Jillian Dempsey, and their daughter Talula.

Patrick and Jillian Dempsey first met in 1994 when the "Grey's Anatomy" star was a client at his future wife's hair salon. The couple's marriage has not always been perfect, and they nearly split ...

NPR's Leila Fadel talks with actor Patrick Dempsey about his efforts to raise money for cancer treatment and prevention.

Patrick Dempsey is the proudest papa in the world as his twin sons make a momentous big step in their futures: high school graduation! And in the rare photo, we see which twin looks like which ...

Learn more about Patrick Dempsey’s wife, Jillian Dempsey (née Fink), who married ‘McDreamy’ in 1999. Here’s what we know about the couple, from kids to divorce filings.

Patrick Dempsey reveals why he will not be reprising the role of Mark Kincaid in Scream 7 despite speculation that he was Sidney Prescott's husband.

Patrick Dempsey is teasing that he might be involved in Scream 7 and will reprise his role in the slasher film.

Patrick "McDreamy" Dempsey credits his acting career for helping him prepare for his return to racing. Fans can follow that journey in a new documentary.

Patrick Dempsey says his eyes were opened when his mom was diagnosed with cancer. In an exclusive conversation with PEOPLE, the actor, 58, speaks candidly about his mom Amanda Dempsey's cancer ...