Lionel Messi will miss Inter Miami's crucial Leagues Cup match against Pumas UNAM due to a muscle issue, coach Javier Mascherano said Tuesday.Inter Miami likely need a victory over Pumas in their group stage finale to reach the quarter-finals of the Leagues Cup,

Lionel Messi was on a generational run with Inter Miami, dominating both MLS and the League’s Cup. But in the second match against Necaxa, everything changed as Messi picked up an injury and left the field just 11 minutes into the game.

Lionel Messi exited Saturday night's Leagues Cup match against visiting Necaxa in the 11th minute due to a right leg injury. After Inter Miami completed its 2-2 draw, manager Javier Mascherano declared Messi felt "hamstring discomfort.