The Greater Cincinnati Northern Kentucky Stroke Study—a population-based epidemiological study—found that between 1993/1994 and 2005, the mean age of those who have a stroke declined by 2 years, while ...

Lipid uptake and metabolism are central to the function of organs such as heart, skeletal muscle, and adipose tissue. Although most heart energy derives from fatty acids (FAs), excess lipid ...

Appendix 1. Author Relationships With Industry and Other Entities (Relevant) e53 Appendix 2. Reviewer Relationships With Industry and Other Entities (Comprehensive) e55 When developing recommendations ...

In this investigation 52 547 patients with a new atrial fibrillation diagnosis between 2010 and 2020 were retrospectively identified. We applied a type of artificial intelligence called tabular ...

Smooth muscle cell migration occurs during vascular development, in response to vascular injury, and during atherogenesis. During atherogenesis, vascular smooth muscle (VSM) cells migrate to populate ...

The development of pulmonary hypertension (PH) is common and has adverse prognostic implications in patients with heart failure due to left heart disease (LHD), and thus far, there are no known ...

Background— The ability to derive human induced pluripotent stem (hiPS) cell lines by reprogramming of adult fibroblasts with a set of transcription factors offers unique opportunities for basic and ...

BACKGROUND: Mechanisms of benefit with SGLT2is (sodium-glucose cotransporter-2 inhibitors) in heart failure (HF) remain incompletely characterized. Dapagliflozin alters ketone and fatty acid ...

Statins are powerful lipid-lowering drugs that inhibit cholesterol biosynthesis via downregulation of hydroxymethylglutaryl coenzyme-A reductase. 1 They are largely used in patients with or at risk of ...

Measurement of blood pressure (BP) in the upright posture is recommended by all hypertension guidelines to detect orthostatic hypotension especially in elderly patients. 1 However, a number of studies ...

There are differences between women and men in the pathogenesis of atherosclerotic coronary artery disease, clinical presentation, and even prognosis. 11, 12, 13 Despite the lower prevalence of ...

Resistant hypertension is defined as failure to achieve goal blood pressure (BP) <140/90 mm Hg (or <130/80 mm Hg in patients with diabetes mellitus or chronic kidney disease) in patients with ...