Results of this study demonstrate inconsistent national and international guidelines, thus underscoring the need for robust evidence to define alloimmunization risk and update protocols. Wide ...

Higher relapse rates were associated with c-ANCA/PR3 positivity and granulomatosis with polyangiitis phenotype. In a retrospective study of patients with antineutrophil cytoplasmic (ANCA)-associated ...

I like to play games. The Words With Friends app and online puzzles, like Connections on the New York Times app, keep me thinking. Online games can be important to someone with multiple sclerosis (MS) ...

The SERPINA1 Pi*MZ genotype was associated with increased risks of HCC development in univariable, as well as in multivariable analysis. Carriers of the SERPINA1 Pi*MZ genotype with alpha-1 ...

The edited cells exhibited higher levels of normal liver genes and were better able to resist Cu toxicity, indicating restoration of ATP7B activity. CRISPR/Cas9-mediated gene editing can successfully ...

Recurrent hypoglycemic coma episodes may lead to a primary biliary cholangitis diagnosis. In JCEM Case Reports, Liu and colleagues presented the rare case study of a patient with recurrent ...

Longitudinal follow-up data showed a strong positive correlation between higher let-7c-5p expression and longer time to subsequent ACS events. Higher circulating levels of microRNA let-7c-5p may be ...

Organ-specific symptoms and physical functioning were the domains that showed the greatest improvement. Mepolizumab therapy is associated with a significant improvement in quality of life among ...

Tumor resection led to complete resolution of the patient’s skin symptoms. Granulocyte colony-stimulating factor (G-CSF)-producing tumors should be considered in patients with treatment-resistant or ...

Nearly all (96%) patients with active AAV enrolled in the study achieved remission, with a median time to remission of 77 days. Early glucocorticoid withdrawal is feasible and was well tolerated in ...

It is challenging to quantify the theoretical risk for alloimmunization in the first trimester of pregnancy. To date, no study has conducted a specific assessment of the use of Rhesus (Rh) D immune ...

The study did not find significant changes in weight or body mass index of children with achondroplasia after 24 months of vosoritide treatment. In addition to significantly increasing height over a 2 ...