Protein C combines with protein S and feeds back to inhibit the clotting cascade. Similar to heparin, numerous advantages are associated with using warfarin to treat and prevent thromboembolic ...

Patients can receive anticoagulants, such as heparin ... and expression of a tissue factor that initiates the coagulation ...

Researchers evaluated a drug that represents a new class of anticoagulants known as Factor XI inhibitors for treating patients with atrial fibrillation as part of the AZALEA-TIMI 71 Study.

Anticoagulants interfere with the clotting cascade, a series of events involving factors that lead to clotting. There are different types of anticoagulants based on their mechanism of action ...

Antidotes provide a direct way to counteract acute adverse effects of a drug; for example, protamine can be used to combat bleeding due to administration of the anticoagulant heparin. However, the ...