Heparin. UFH is one of two agents that comprise conventional anticoagulant therapy. It is considered a natural agent and has been the standard of care for many years. Its mechanism of action is ...

Low molecular weight heparin (LMWH) is an anticoagulant injected subcutaneously ... While similar in mechanism to unfractionated heparin, LMWH is cleared renally, has a much longer half-life ...

To understand the pharmacology and mechanism of action of ... Interactions of anticoagulants with thrombin. Panel A shows heparin bound to thrombin at exosite 2 and to antithrombin III.

That said, non-heparin anticoagulants are expensive and hard to monitor, so clinicians want to reserve them for the patients who need them for safety. Adding to the complexity, two different lab ...