Importance Vigilant clinical assessment is the key to preventing complications, including death, in infants at risk of neonatal withdrawal syndrome. The eat, sleep and console (ESC) is proposed as an ...

Objective Growing evidence suggests that coeliac disease (CeD) is more common in patients with inflammatory bowel disease ...

Background We assessed the biopsychosocial needs and key health drivers among children living with a common chronic illness, as baseline for a cluster randomised controlled trial of a child health ...

Introduction This study reviews the first 3 years of delivery of the first National Health Service (NHS)-commissioned trio rapid whole genome sequencing (rWGS) service for acutely unwell infants and ...

Correspondence to: Prof. M Levin, Department of Paediatrics, Faculty of Medicine, Imperial College of Science, Technology & Medicine, Norfolk Place, London W2 1PG, UK; m.levin{at}ic.ac.uk Neisseria ...

Background The evidence base to guide the pharmacological management of tone and abnormal movements in cerebral palsy (CP) is limited, as is an understanding of routine clinical practice in the UK. We ...

1 Department of Paediatric Endocrinology, University Hospital Southampton, Southampton, UK 2 Department of Endocrinology and Diabetes, Birmingham Children's Hospital NHS Foundation Trust, Birmingham, ...

Correspondence to Dr Mahjabeen Shah, School of Life Sciences, Kingston University, London KT1 2EE, UK; mahjabeen.shah{at}kingston.ac.uk Objectives To develop waist circumference (WC) centile curves ...

5 Norfolk and Norwich University Hospitals NHS Foundation Trust, Norwich, UK Background Idiopathic intracranial hypertension (IIH) is a potentially disabling condition. There is a lack of evidence and ...

1 Genetic Medicine, University of Manchester, Manchester Academic Health Science Centre, Central Manchester University Hospitals NHS Foundation Trust, St Mary's Hospital, Manchester, UK 2 Genetic and ...

Background: A phenylalanine-free amino acid based protein substitute is necessary to provide the major source of protein in phenylketonuria (PKU). Protein substitutes in PKU are usually given as ...

Correspondence to Dr Richard Churchill, Nottingham City General Practice Alliance, Nottingham, NG1 6LD, UK; richard.churchill{at}nhs.net Objective To determine views and experiences of babies, ...