Patients with NMOSD had significantly reduced functional connectivity in the sensorimotor, lateral and left dorsal visual, and executive control networks in the brain compared to healthy people.

Significant gaps remain in our collective ability to treat generalized pustular psoriasis (GPP) flares in a timely and effective manner. Medicine in the mid-20th century was mostly a hit-and-miss ...

For the last 3 years, the PBC Foundation, based in Edinburgh, Scotland, has conducted an annual summit that addresses the challenges and potential remedies for those living with primary biliary ...

New research shows that obese patients had a higher risk of comorbidities and poorer functional status. A simple definition of an epidemic is an illness that becomes unexpectedly widespread within a ...

Thrombosis is a key manifestation of paroxysmal nocturnal hemoglobinuria and can sometimes be life-threatening. Thrombosis is one of the primary manifestations of paroxysmal nocturnal hemoglobinuria ...

Diagnosing systemic vasculitis remains a considerable clinical challenge, as does managing this disease after diagnosis. The general physician should have a working knowledge of vasculitis, including ...

In addition to lower complement levels, patients with ITP had elevated CRP levels compared with healthy controls. Serum complement levels could indicate disease activity in patients with immune ...

Navepegritide was well tolerated, with a safety profile comparable to placebo and low rates of injection site reactions. Navepegritide significantly improved growth outcomes in children with ...

Higher relapse rates were associated with c-ANCA/PR3 positivity and granulomatosis with polyangiitis phenotype. In a retrospective study of patients with antineutrophil cytoplasmic (ANCA)-associated ...

The disease burden in PAH is both personal and macroeconomic; both have to be approached with strategy, tact, and empathy. In scientific literature, “disease burden” usually refers to one of two ...

This novel method achieves 100% sensitivity and 97.5% specificity for the detection of clonal rearrangement, while delivering mutational status concordant with Sanger in 99.1% of cases. In a cohort of ...

Results of this study demonstrate inconsistent national and international guidelines, thus underscoring the need for robust evidence to define alloimmunization risk and update protocols. Wide ...