Patients with NMOSD had significantly reduced functional connectivity in the sensorimotor, lateral and left dorsal visual, and executive control networks in the brain compared to healthy people.

Significant gaps remain in our collective ability to treat generalized pustular psoriasis (GPP) flares in a timely and effective manner. Medicine in the mid-20th century was mostly a hit-and-miss ...

For the last 3 years, the PBC Foundation, based in Edinburgh, Scotland, has conducted an annual summit that addresses the challenges and potential remedies for those living with primary biliary ...

New research shows that obese patients had a higher risk of comorbidities and poorer functional status. A simple definition of an epidemic is an illness that becomes unexpectedly widespread within a ...

Diagnosing systemic vasculitis remains a considerable clinical challenge, as does managing this disease after diagnosis. The general physician should have a working knowledge of vasculitis, including ...

In addition to lower complement levels, patients with ITP had elevated CRP levels compared with healthy controls. Serum complement levels could indicate disease activity in patients with immune ...

Thrombosis is a key manifestation of paroxysmal nocturnal hemoglobinuria and can sometimes be life-threatening. Thrombosis is one of the primary manifestations of paroxysmal nocturnal hemoglobinuria ...

Navepegritide was well tolerated, with a safety profile comparable to placebo and low rates of injection site reactions. Navepegritide significantly improved growth outcomes in children with ...

Pulmonary rehabilitation is an underutilized tool in the management of PAH. Referrals to pulmonary rehabilitation among patients with pulmonary arterial hypertension (PAH) are relatively low despite ...

Patients with MF who did not receive ruxolitinib had higher levels of the inflammatory cytokines CD25, REG3A, IL18, and ST2 than those treated with ruxolitinib at baseline. The baseline cytokine ...

Higher relapse rates were associated with c-ANCA/PR3 positivity and granulomatosis with polyangiitis phenotype. In a retrospective study of patients with antineutrophil cytoplasmic (ANCA)-associated ...

The disease burden in PAH is both personal and macroeconomic; both have to be approached with strategy, tact, and empathy. In scientific literature, “disease burden” usually refers to one of two ...