The Detroit Lions will know how meaningful their matchup with the San Francisco 49ers on Monday night will carry before they ...

Detroit Lions defensive coordinator Aaron Glenn called San Francisco 49ers TE George Kittle 'the best tight end in the game.' ...

Here is how to watch the rematch of last year's NFC Championship game between the Lions and 49ers on television: ...

Week 17 of "Monday Night Football" features the Detroit Lions and the San Francisco 49ers. Check out how to watch on ESPN.

The 49ers are eliminated from the playoffs. But don't tell Kittle or Samuel that, with both studs having two of their best ...

Geoff Schwartz is back with his best bets for NFL Week 17. Find out why he's backing the Lions in San Francisco and why he ...

All the way back in January, Brock Purdy and the San Francisco 49ers secured their biggest win of the season, beating the ...

The San Francisco 49ers face unexpected challenges this season, with a 6-9 record and playoff hopes dashed. Defensive star ...

Detroit Lions head coach Dan Campbell made his intentions clear when asked about Monday night's primetime NFC Championship ...

When it comes to injuries, the Detroit Lions haven't gotten a lot of good news this season. However, on their Friday practice ...

Detroit Lions aim for NFC's top seed in rematch with San Francisco 49ers, while San Francisco plays out disappointing season.