Alpha-thalassemia minima/silent carrier: Only one of your four alpha-globin genes is affected. You generally won’t have any symptoms and may not have any noticeable laboratory findings.

At phenotypic level, the carrier states are divided into silent carrier and - alpha/-alpha thalassemia trait. The silent carrier state most frequently results from the presence of a single alpha ...

One parent of a patient with Hb H disease, a doubly heterozygous form of alpha thalassemia, is usually hematologically normal, whereas the other has microcytosis (alpha thalassemia trait). 1 The ...

Genes (two from each parent) Condition Description; α α / α – (1 missing) alpha-thalassemia carrier: You’re a silent carrier with no significant symptoms.

World Thalassemia Day was observed on 8 May. India records between 10,000 and 15,000 new cases of Thalassemia Major every year, with national carrier rates estimated at 3 to 4 per cent, and as ...

Alpha thalassemia silent carrier-When one out of the four alpha-globin genes is missing. The other three function normally, the blood cells become comparatively smaller and being a silent ...

For instance, in alpha minor thalassemia silent carrier, with one gene missing in the red blood cells, patients majorly experience anaemia and fatigue while in the other type of alpha thalassemia ...

Alpha thalassemia has four subtypes, each representing a different combination of affected genes: silent carrier, alpha thalassemia trait, hemoglobin H disease, and Bart's hydrops fetalis.

Alpha-thalassemia is particularly common among certain populations of Southeast Asian descent. There is also a high number of carriers in Sub-Saharan Africa and Western Pacific regions.

Dr. Peng Zhiyu, Vice President of BGI Genomics, recently emphasized that Thalassemia is highly preventable with carrier screening tests using Next-Generation Sequencing (NGS) technology. The ...