If patients did not meet the BP goal with the maximum tolerated dose of the initial medication, an open-label step 2 agent (atenolol, 25-100 mg/day; reserpine, 0.05-0.2 mg/day; or clonidine ...
The VALUE trial compared the effect of an ARB (valsartan) with a CCB (amlodipine), both in the whole cohort as well as in the diabetic subgroup. No significant difference in the composite cardiac ...