Management Adjustment of dopaminergic therapy (carbidopa–levodopa and entacapone) to minimize motor fluctuations and camptocormia. ... the mechanism of pathogenesis remains unclear.

To further investigate the mechanism of quenching for monomer crowders and polymeric dextran 40, a temperature variation study was carried out using 10 μM Trp and 300 mg/mL crowders by varying the ...

The cellular composition and underlying spatiotemporal transformation processes of subchondral bone in osteoarthritis (OA) remain unknown. Herein, various cell subsets from tibial plateau of patients ...

Authors and Disclosures. Lauren C Seeberger, MD Medical Director, The Movement Disorders Center at the Elks, 600 N. Robbins Rd, Boise, ID 83702, USA. Tel.: +1 208 489 4599, Fax: +1 208 489 4051 ...

Since the 1960s, levodopa (LDA) has been the standard drug for treating of Parkinson’s disease. In this study, a novel benzothiadiazole-based conjugated microporous polymer-coated graphene ...

Background Recently, symptoms similar to addictive drug withdrawal have been reported in a structured longitudinal study of patients with idiopathic Parkinson's Disease (PD) withdrawing from dopamine ...

BEIJING -- China is set to establish a unified cross-basin ecological compensation mechanism for the mainstreams of the Yangtze and Yellow rivers by 2027, as part of its broader efforts to improve ...

The switch from fetal γ-globin to adult β-globin is controlled by BCL11A. Genetic manipulation of BCL11A improves disease outcomes by turning γ-globin expression back on to compensate for ...

The latest version of the 'Crocodilus' Android malware has introduced a new mechanism that adds a fake contact on the infected device's contact list to deceive victims.