[Mahajan A, et al. Antiarrhythmic Drugs. 2011;5a] Class IC drugs block cardiac sodium channels and have no effect on the action potential. Class IC drugs are commonly used to maintain sinus rhythm ...

Mexiletine is an oral formulation of a class 1C antiarrhythmic drug (like lidocaine) which can be used in the outpatient setting.

Current antiarrhythmic drugs for AF have limited ... and atrial remodeling. Class III drugs sotalol, dofetilide and ibutilide target reentry by prolonging the atrial effective refractory period ...

Propafenone HCl 225mg, 325mg, 425mg; ext-rel caps. 225mg: White capsule imprinted in red with GS EUG followed by 225. 325mg: White capsule imprinted in red with GS F1Y followed by 325; single red ...

Caution with drugs that lower seizure threshold (eg ... thioridazine), β-blockers (eg, metoprolol), Class 1C antiarrhythmics (eg, propafenone, flecainide); consider dose reduction.

However, the rhythm control strategy can be a problem because antiarrhythmic drugs are usually necessary for restoring and maintaining normal heart rhythm. These drugs tend to be relatively ...