Lupus can be debilitating and sometimes deadly for the 3 million people who have it. A treatment called CAR T appears to stop ...

WILLOW (NCT05162586) is a randomized, double-blind, placebo-controlled Phase 2 proof of concept and dose-finding study designed to evaluate the efficacy and safety of enpatoran in patients with ...

Connective tissue diseases are a heterogeneous group of autoimmune disorders that affect any of the body's connective tissues. These disorders can be inherited or acquired, and can present with a ...

Nonsteroidal anti-inflammatory drugs (NSAIDs): These medications can help reduce pain and swelling in joints and muscles. Corticosteroids: Corticosteroids, namely prednisone, can reduce swelling and ...

A recent report suggests that patients with newly diagnosed SLE have significantly greater prevalence of hypocomplementemia than patients with conditions that mimic SLE, including undifferentiated ...

The findings suggest that treatment resulted in marked improvement in disease activity, effective B cell depletion and recovery of naive B cell phenotype, and a safety profile that is in line with ...

Pharmacological Approach to Managing Childhood-Onset Systemic Lupus Erythematosus During Conception, Pregnancy and Breastfeeding. Paediatr Drugs. Furie RA, Bruce IN, Dörner T, et al. Phase 2 ...

In the study, DZP demonstrated significant clinical improvements in disease activity in people living with moderate-to-severe systemic lupus erythematosus (SLE), as measured by the British Isles ...

A connective tissue or autoimmune disease. Chemical exposure. Cigarette smoking. Injury or trauma. Repetitive actions, such as typing or using tools that vibrate, such as a jackhammer. Side effects ...

“Much more work and research funding are needed to fully understand the pathogenesis of disease, the mechanisms of tissue injury, and the underlying genetic predispositions” linking the 2 disease ...