Researchers have identified ways in which chemotherapy can damage healthy cells and found that some drugs can add decades of ...

For the first time, scientists have systematically studied the genetic effects of chemotherapy on healthy tissues. Researchers from the Wellcome Sanger Institute, the University of Cambridge, ...

Researchers have uncovered new patterns of DNA damage associated with specific chemotherapy drugs to guide cancer treatment for less effects.

As part of Cancer Grand Challenges team Mutographs, the researchers uncovered new patterns of DNA damage, or mutational signatures ... all of the main chemotherapy classes, including alkylating agents ...

FDA decision will enable Iksuda to expand its ongoing clinical trial in the US, Australia and Singapore. Preliminary data from an ongoing dose-escalation study of IKS014 has shown ...

A new study reveals that blocking ribosomal RNA production rewires cancer cell behavior and could help treat genetically ...

Chlorambucil (N,N-bis(2-chloroethyl)-p-aminophenylbutyric acid) is a bifunctional alkylating drug belonging to the nitrogen mustard group and is widely used as an anticancer agent. As the antitumor ...

Small molecule complexes with DNA that incorporate linking water molecules are rare, and the DB921-DNA complex has provided a unique and well-defined system for analysis of water-mediated binding in ...