Denver was once again in President Donald Trump's sights as he directed federal immigration officers to prioritize deportations from Democratic-run cities following large-scale protests across the U.S.

Police in Denver responded in full force to marches downtown after an earlier peaceful protest at the Colorado State Capitol.

Denver Mayor Mike Johnston said the city doesn’t need the National Guard or federal enforcement to handle demonstrations and protests, and will oppose it.

More than a dozen rallies across the state were peace. Police used pepper balls and smoke on one group in Denver.

Denver police arrested several demonstrators during a march against ICE raids in downtown Denver Tuesday night.

A group marched to the ICE facility in Aurora on Monday in solidarity with protestors in Los Angeles. Another rally is expected to happen today at the state capitol in Denver.