Early findings showed EXG-34217 successfully lengthened CD34+ cell telomeres by 1.24-fold ex vivo in a patient with dyskeratosis congenita, a telomere biology disorder that can lead to bone marrow ...

ALTERNATIVE MEDICATIONS: For those unable to afford ATG or BMT, oral medications like Danazol and Cyclosporin can be considered, potentially benefiting about 30% of patients. LEADING TREATMENT ...

One of the telomere disorders frequently resulting from the condition is known as dyskeratosis congenita, which can lead to bone marrow failure and affect the skin and other organs. Research by ...

What Is Oral Lichen Planus? Oral lichen planus is a long-lasting disease that affects your mouth, causing symptoms such as painful white patches, redness, and swelling. It doesn't go away ...

Oral chemotherapy kills or weakens cancer cells. It comes in the form of a pill, liquid, or tablet that a person swallows or places under the tongue to dissolve. It is not suitable for all stages ...

Diagnosis Recessive myotonia congenita (Becker's disease). Management Explanation of the nature of the disease and treatment with mexiletine 200 mg twice daily. A 56-year-old woman with a history ...

TBDs, such as dyskeratosis congenita, can lead to serious conditions including bone marrow failure due to severely affecting the ability of hematopoietic stem cells (HSCs) to produce blood cells.

Hospitals in England have been hit by a storm of norovirus infections as the number of beds taken up by patients with the virus reached a record high last week. An average 1,160 patients a day were in ...

Oral cancer is a type of head and neck cancer that develops when abnormal cells within the lining of the cheeks, gums, roof of the mouth, tongue, or lips grow uncontrollably. Oftentimes, oropharyngeal ...

You must provide allergen information: before the purchase of the food is completed - this can be in writing (on a website, catalogue or menu) or orally (by phone) when the food is delivered - this ...

Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, ...