One of the telomere disorders frequently resulting from the condition is known as dyskeratosis congenita, which can lead to bone marrow failure and affect the skin and other organs. Research by ...

Early findings showed EXG-34217 successfully lengthened CD34+ cell telomeres by 1.24-fold ex vivo in a patient with dyskeratosis congenita, a telomere biology disorder that can lead to bone marrow ...

TBDs, such as dyskeratosis congenita, can lead to serious conditions including bone marrow failure due to severely affecting the ability of hematopoietic stem cells (HSCs) to produce blood cells.

Aplastic anaemia is a rare but serious blood disorder in which the bone marrow fails to produce enough blood cells—red blood cells, white blood cells, and platelets. This condition can lead to fatig ...

There are typically no vacuolated or dyskeratotic cells in the spinous layer. Because the histologic characteristics of spiny keratoderma are distinct, microscopy is useful in the diagnosis of ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Widespread control of gene expression through ...