One of the telomere disorders frequently resulting from the condition is known as dyskeratosis congenita, which can lead to bone marrow failure and affect the skin and other organs. Research by ...
Aplastic anaemia is a rare but serious blood disorder in which the bone marrow fails to produce enough blood cells—red blood cells, white blood cells, and platelets. This condition can lead to ...
Early findings showed EXG-34217 successfully lengthened CD34+ cell telomeres by 1.24-fold ex vivo in a patient with dyskeratosis congenita, a telomere biology disorder that can lead to bone marrow ...
TBDs, such as dyskeratosis congenita, can lead to serious conditions including bone marrow failure due to severely affecting the ability of hematopoietic stem cells (HSCs) to produce blood cells.
TBDs, such as dyskeratosis congenita, can lead to serious conditions including bone marrow failure due to severely affecting the ability of hematopoietic stem cells (HSCs) to produce blood cells.
We conducted a comprehensive retrospective review of electronic medical records from outside facilities and those available at Texas Children's Hospital (Houston). All the co-authors were aware of the ...
Pulmonary fibrosis is a fatal lung disease characterized by fibrotic foci and inflammatory infiltrates. Short telomeres can impair tissue regeneration and are found both in hereditary and sporadic ...
We dissected the importance of human telomerase biogenesis and trafficking pathways for telomere maintenance. Biological stability of human telomerase RNA (hTR) relies on H/ACA proteins, but other ...
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