Ejection fraction between 30%–39% Based on the computed sample sizes for the first and second objectives, an appropriate sample size to meet both objectives were 350 patients. With an incomplete and ...

Flow chart of participant selection and experimental procedures ... including left ventricular end-diastolic volume (LVEDV), end-systolic volume (LVESV), stroke volume (LVSV), ejection fraction (LVEF) ...

Left ventricular ejection fraction was measured by the M-mode echocardiograph ... USA). Values that are out of range or represent errors of faulty logic are avoided by double check. Until now, the ...

The Food and Drug Administration (FDA) has accepted for Priority Review the supplemental New Drug Application (sNDA) for finerenone for the treatment of ...

"The completion of enrollment in the Phase 1/2a trial marks a crucial milestone for this cardiac gene therapy trial in patients with heart failure with reduced ejection fraction (HFrEF).

Medera is a clinical-stage biopharmaceutical company focused on targeting difficult-to-treat and currently incurable diseases by developing a range of next-generation therapeutics. Medera operates via ...

The findings showed: Significant improvements from placebo in left ventricular systolic function (increased left ventricular ejection fraction [LVEF] of 3.76% and decreased left ventricular end ...

A normal ejection fraction ranges from 55% to 70%. In systolic heart failure, that number often drops below 40%, indicating significantly reduced pumping capacity. Beyond traditional imaging ...

Patients with ejection fraction <40% were excluded ... NYHA class Mean 26.2 mo (range 12–30) Primary: 23.6% in perindopril group vs 25.1% in placebo (HR 0.92; 95% CI 0.70 to 1.21; p = 0.545 ...

Researchers also observed improvements in the left ventricle, including better ejection fraction and reverse remodeling. In terms of overall survival rates, the tricaprin group had 100% three-year ...

Total scores range from 0 to 74 with higher scores ... 001) and left ventricular ejection fraction measures when compared with an external comparator dataset of similar DMD patients.