Patrick Dempsey joined the cast of Grey's Anatomy in Season 1 as Derek Shepherd (a.k.a. McDreamy), a neurosurgeon and Meredith Grey's love interest. Getty Images ...

The series revitalized Patrick Dempsey's career and made household names out of the Season 1 cast. Grey's Anatomy was the show you had to watch every Sunday night (yes, it used to air on Sundays ...

Grey’s Anatomy, which has successfully reinvented itself multiple times going through numerous casting changes, is headed to another transformational season, with star Ellen Pompeo scaling back ...

Grey’s Anatomy is returning to screens for season 22 this fall, months after fans were left on a jaw-dropping cliffhanger ...

"Grey's Anatomy" is shaking things up this season. The longest-running primetime medical drama on television, which premiered way back in 2005 and has captivated fans ever since, kicks off its ...

Like any medical drama, Grey's Anatomy also has some recurring things or storylines that end up getting repeated season after season, for good or bad.

The 15 seasons of Grey's Anatomy that have aired so far have seen dozens of doctors come and go from the cast, with many guest stars rising through the ranks to become main characters. And Season ...

"Grey's Anatomy" Season 17 featured the return of Patrick Dempsey, McDreamy, in a dream sequence. ABC. Grey's Anatomy put its most surprising return first, as McDreamy himself returned to see his ...

As Grey's Anatomy barrels along through its second decade on the air, it's only natural that the actors who make up its cast have changed. Yes, ...