A lifesaving antidote is unavailable or ineffective in preventing toxicosis ... which generally should not exceed 10% to 15% of patient blood volume), hypothermia, hemorrhage (excessive heparin effect ...

After more than 70 years of effective clinical use, heparin remains the most common anticoagulant in use and one of the most commonly prescribed drugs to hospitalized patients. However ...

Meridian Medical Technologies, a unit of CDMO Kindeva, snared a $129 million contract to supply the United States with the chemical nerve agent antidote autoinjector DuoDote. The FDA-approved ...

THE BITE of a black mamba (pictured) causes respiratory muscular paralysis. And death. Disturb a Russell’s viper and the encounter may lead to kidney damage and excess bleeding. And death. As to ...

Although seemingly more convenient, idraparinux is potentially unsafe in cancer patients due to its long half-life of approximately 4 days and the lack of an available antidote for reversal of the ...

AstraZeneca's anticoagulant reversal agent Andexxa was given an accelerated approval by the FDA in 2018, but the company's plan to get that upgraded to a full approval is facing some pushback.

According to the show, the purpose of Foxglove was to create antidotes for bioweapons that could be used against the US. However, to find the antidote, they also had to have the bioweapons. From here, ...

Consider whether there is a real need to stop anticoagulation for the scheduled procedure. Do not use low molecular weight heparin (LMWH) to bridge direct oral anticoagulants. Do not use therapeutic ...