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CorMedix is a bio-pharmaceutical company that produces DefenCath, an antimicrobial catheter lock solution containing ...
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Additionally, the efficiency of these heparin solutions is not as consistent (ranging from 50% to 73%), while that of DefenCath is at 71%.
Preservative-Free Heparin Lock Flush Solution(Hep Lock) generic is an anionic mucopolysaccharide, prescribed for keeping IV catheters open and flowing freely in blood sampling.
The FDA has approved taurolidine plus heparin (DefenCath®) catheter lock solution to reduce catheter-related bloodstream infections in patients receiving maintenance hemodialysis via a central venous ...
The approval is based on positive results from the phase 3 LOCK IT-100 trial (ClinicalTrials.gov Identifier: NCT02651428), which showed that taurolidine plus heparin significantly reduced the risk ...
When compared with the anticoagulant heparin alone, significantly fewer patients receiving the taurolidine-heparin solution had a catheter‐related bloodstream infection (8% vs 2%, respectively ...