An intestinal stem-cell pool is maintained through migration. Stem cells come in many guises, from the multifunctional cells of early embryos to the more restricted variety found in adult tissues.

Intestinal cells arise from stem cells that lie in indentations (the crypts) of the intestinal wall. These intestinal cells then migrate up the intestinal villi. During their migration, ...

Intestinal cells can change specializations during their lives. The BMP signaling pathway -- an important communication mechanism between cells -- appears to be the driver of these changes ...

“Genetic photoconversion experiments revealed that fasting induced the migration of intestinal ILC2s to the pancreas, which was associated with the expression of genes associated with intestinal ...

Reference: Niec RE, Chu T, Schernthanner M, et al. Lymphatics act as a signaling hub to regulate intestinal stem cell activity. Cell Stem Cell. 2022;29(7):1067-1082.e18. doi: ...

More information: Lulu Huang et al, Tuft cells act as regenerative stem cells in the human intestine, Nature (2024). DOI: 10.1038/s41586-024-07952-6 Provided by Hubrecht Institute ...

More than 4000,000 people in Germany are affected by the chronic inflammatory bowel diseases Morbus Crohn or ulcerative colitis. Patients often suffer from flare-ups, which damage intestinal ...

Health Intestine cell transplant may one day help ease digestive issues. Patches of intestinal tissue grown from the cells of mice contract similarly to the muscles in the digestive tract.

In aquaculture, feed-induced chronic inflammation of the intestinal mucosa is particularly common, and the intestinal mucosal immune barrier is often the first place where aquatic pathogens, such ...