One in eight women in Scotland will be diagnosed with breast cancer but a breakthrough could be on the horizon ...

DOI: 10.1038/s41586-025-09097-6 Memorial Sloan Kettering Cancer Center researchers have identified a metabolic switch that determines whether intestinal stem cells become absorptive or secretory ...

Using advanced cell-tagging methods, the team labeled ILC2 cells in the gut, giving them a glow-in-the-dark marker. After fasting, they found these cells had travelled to the pancreas.

Methods: We determined the effects of arginine on cultured intestinal cell migration, NO production, polyamine levels, and activation of focal adhesion kinase, a key mediator of cell migration.

Tuft cells are present throughout the intestinal tract as well as in many other organs. Most insights into the function and ...

By utilizing intestine-wide cell imaging, the researchers found that the nutrient adaptation of stem cell size and the resulting differentiation vary in different regions of the gut.

Looking closely at the intestines, Colozza saw that intestines lacking Rnf43 were full of a specific type of secretory cells, the Paneth cells. Intestines lacking Daam1, on the other hand ...

But as the intestines age, they become weaker barriers, allowing substances that may hasten the aging process to pass through their walls and into the rest of the body—and they age faster than ...

Making tissue patches from the cells found in a healthy intestine could one day treat certain digestive conditions, according to a study in mice. The tube-shaped intestines in our bodies contain ...

More information: Wenya Shu et al, A multiscale whole-cell theory for mechanosensitive migration on viscoelastic substrates, Biophysical Journal (2022). DOI: 10.1016/j.bpj.2022.11.022 ...

Rockefeller scientists found that lymphatic capillaries—fine vessels that transport immune cells and drain fluids from tissues—represent a signaling hub that communicates with stem cells to regulate ...

A dynamic mode of stem-cell regulation has been discovered. Intestinal stem cells use migration to maintain a large pool of multifunctional cells, perhaps endowing the organ with robust responses ...