World Down Syndrome Day is right around the corner, and I invite you to join us in celebrating on March 21! This special day ...

Down Syndrome, known as Trisomy 21, is a genetic disorder caused by an extra chromosome 21. It affects facial appearance, ...

The "rocking" of colorful, mismatched socks every March 21 might seem like a weirdly random tradition on a weirdly random day ...

Players across both our Men’s and Women’s First Team wore colourful, mismatched socks during training on Wednesday in support of Down Syndrome Awareness. People across the world take part in the ...

Abstract Rare and common genetic variants contribute to the risk of atrial fibrillation (AF). Although ion channels were among the first AF candidate genes identified, rare loss-of-function variants ...

Investigators led by CHLA’s Jonathan D. Santoro, MD, published a new research study that links Down syndrome Regression ...

MRI findings uncover an unexpected mismatch between Alzheimer’s pathology and cognitive function in a unique case study.

According to the Centers for Disease Control and Prevention ( CDC ), about 1 in 700 babies in the U.S. is born with Down syndrome, which equates to about 5,100 births per year. While many cases are ...

A new research study led by Jonathan D. Santoro, MD, Director of the Neuroimmunology Program at Children's Hospital Los Angeles, shows evidence of dysfunction of the blood-brain barrier and ...